Elevated 68 Ga-FAPI Activity in Leiomyosarcoma

Clin Nucl Med. 2024 May 1;49(5):e197-e198. doi: 10.1097/RLU.0000000000005032. Epub 2024 Jan 23.

Abstract

Leiomyosarcoma is an aggressive subtype of soft tissue sarcoma with frequent metastatic relapse after curative surgery. Herein, we report the 68 Ga-FAPI PET/CT findings in a 45-year-old woman with leiomyosarcoma. 68 Ga-FAPI-04 PET/CT detected increased FAPI uptake in abdominal leiomyosarcoma and liver metastases. The positive findings of 68 Ga-FAPI in this case highlighted that 68 Ga-FAPI may have potential value in the evaluation of leiomyosarcoma.

Publication types

  • Case Reports

MeSH terms

  • Biological Transport
  • Female
  • Fluorodeoxyglucose F18
  • Gallium Radioisotopes
  • Humans
  • Leiomyosarcoma* / diagnostic imaging
  • Middle Aged
  • Positron Emission Tomography Computed Tomography
  • Sarcoma*

Substances

  • Gallium-68
  • Gallium Radioisotopes
  • Fluorodeoxyglucose F18