We report fatal West Nile virus (WNV) infection in a 7-year-old mare returning to the United Kingdom from Spain. Case timeline and clustering of virus sequence with recent WNV isolates suggest that transmission occurred in Andalusía, Spain. Our findings highlight the importance of vaccination for horses traveling to WNV-endemic regions.
Keywords: Spain; United Kingdom; WNV; West Nile virus; equine; flavivirus; vector-borne infections; viruses; zoonoses.