Primary malignant melanoma of the female urethra A rare histopathology case report

Anahita Ansari Djafari; Babak Javanmard; Sina Samenezhad; Amir Hossein Eslami; Azadeh Rakhshan

doi:10.1016/j.eucr.2023.102642

Primary malignant melanoma of the female urethra A rare histopathology case report

Urol Case Rep. 2023 Dec 27:52:102642. doi: 10.1016/j.eucr.2023.102642. eCollection 2024 Jan.

Authors

Anahita Ansari Djafari¹, Babak Javanmard¹, Sina Samenezhad¹, Amir Hossein Eslami¹, Azadeh Rakhshan²

Affiliations

¹ Shahid Beheshti University of Medical Sciences Laser Application in Medical Sciences Research Center, Urology, Tehran, Tehran, Iran.
² Department of Pathology, Shohada-e-tajrish Educational Hospital, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Abstract

Malignant melanoma in the urethra is a rare tumor that is difficult to diagnose and treat, leading to a poor prognosis. In this paper, we present the case of a 36-year-old woman with history of invasive rectal adenocarcinoma (PT2N0Mx) who was tumor free for 5 years presented to urology outpatient with history of poor stream, dysuria, and dyspareuria. On examination, there was a huge mass in the meatus of urethra. Urethral malignant melanoma shows a high rate of local recurrence, about 60 % in 1 year. Overall survival in a series of 11 cases at 3 years was 27 %.

Publication types

Case Reports