Identification of Risk Factors for Mastalgia and Its Relationship with Benign or Malignant Breast Diseases

Banu Yigit; Gulhan Kilicarslan; Bulent Citgez

doi:10.14744/SEMB.2023.75002

Identification of Risk Factors for Mastalgia and Its Relationship with Benign or Malignant Breast Diseases

Sisli Etfal Hastan Tip Bul. 2023 Dec 29;57(4):485-494. doi: 10.14744/SEMB.2023.75002. eCollection 2023.

Authors

Banu Yigit¹, Gulhan Kilicarslan², Bulent Citgez³

Affiliations

¹ Department of General Surgery, Elazig Fethi Sekin City Hospital, Elazig, Türkiye.
² Department of Radiology, Elazig Fethi Sekin City Hospital, Elazig, Türkiye.
³ Department of General Surgery, Uskudar University Faculty of Medicine, Memorial Hospital, Istanbul, Türkiye.

Abstract

Objectives: Mastalgia is a medical condition that primarily affects women of all age groups. Affected individuals experience excruciating pain, tightness, or a burning sensation in the breast tissue. The aim of this study is to observe the clinicopathologic features of women with mastalgia and compare these features with asymptomatic cases.

Methods: A total of 524 female patients who applied to the general surgery outpatient clinic were prospectively evaluated. The patients were divided into two groups. Group 1 (G1) included patients with mastalgia, while Group 2 (G2) included asymptomatic patients. The two groups were compared in terms of clinical, radiological, and pathological features.

Results: This study was conducted on 524 women, among whom the prevalence of mastalgia was found to be 61.45%. There were 322 patients in G1 and 202 patients in G2. The mean age was significantly higher in G2 compared to G1 (46.33±10.33 vs. 43.58±10.33, respectively; p=0.001). Premenopausal women rates for G1 and G2 were 73.91% and 59.4%, respectively (p=0.001). The regular exercise rate in G1 was 18.01%, while it was 25.74% in G2 (p=0.034). The past history of breast cancer rate was significantly higher in G2 than in G1 (p=0.015). The consumption of analgesics was significantly lower in G2 compared to G1 (p=0.05). Non-steroidal anti-inflammatory drugs were the most commonly used analgesic drug class in both groups, with significant intergroup differences (G1: 27.63%, G2: 19.8%, p=0.043). Screening mammography with or without ultrasound examination was performed significantly more often in G2 compared to G1 (66.33% vs. 55.27% and 82.17% vs. 72.98%, p=0.012 and p=0.016, respectively). No significant difference was found concerning the frequency of benign or malignant pathologies between the groups.

Conclusion: Breast pain is common and should be considered physiological without other breast symptoms and after excluding non-breast causes. It is safe to provide symptom control advice and reassurance to patients who have breast pain but do not have signs or symptoms indicating a possible serious underlying condition requiring further medical intervention.

Keywords: Analgesic; breast pain; exercise; mammography; mastalgia; ultrasound.