A novel olfactory biosensor based on ZIF-8@SWCNT integrated with nanosome-AuNPs/Prussian blue for sensitive detection of hexanal

Jing Liu; Yan Ping Chen; Penglin He; Ziyu Ding; Yun Guo; Songhe Cui; Chao Ma; Zhiping Xie; Sun Xia; Yin Zhang; Ye Liu; Yuan Liu

doi:10.1016/j.foodchem.2023.138349

A novel olfactory biosensor based on ZIF-8@SWCNT integrated with nanosome-AuNPs/Prussian blue for sensitive detection of hexanal

Food Chem. 2024 Jun 1:442:138349. doi: 10.1016/j.foodchem.2023.138349. Epub 2024 Jan 19.

Authors

Jing Liu¹, Yan Ping Chen², Penglin He², Ziyu Ding², Yun Guo², Songhe Cui³, Chao Ma², Zhiping Xie³, Sun Xia⁴, Yin Zhang⁵, Ye Liu⁶, Yuan Liu⁷

Affiliations

¹ School of Food Science and Engineering, Ningxia University, Yinchuan 750021, China.
² Department of Food Science & Technology, School of Agriculture & Biology, Shanghai Jiao Tong University, Shanghai 200240, China.
³ School of Life sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.
⁴ School of Agricultural Engineering and Food Science, Shandong University of Technology, Zibo 255049, Shandong Province, China.
⁵ Key Laboratory of Meat Processing of Sichuan, Chengdu University, Chengdu, 610106, China.
⁶ Beijing Engineering and Technology Research Center of Food Additives, School of Food and Health, Beijing Technology and Business University (BTBU), Beijing 100048, China. Electronic address: liuye@th.btbu.edu.cn.
⁷ Department of Food Science & Technology, School of Agriculture & Biology, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address: y_liu@sjtu.edu.cn.

PMID: 38266411
DOI: 10.1016/j.foodchem.2023.138349

Abstract

Hexanal is considered as an important volatile compound indicator for the assessment of freshness and maturity of foods. Therefore, sensitive and stable monitoring of hexanal is highly desired. Herein, an efficient receptor immobilization strategy based on ZIF-8@ Single-walled carbon nanotube (SWCNT) and nanosomes-AuNPs/Prussian blue (PB) was proposed for the development of olfactory biosensors. ZIF-8@SWCNT as dual support materials provided a high density of active sites for nanosomes loading. Moreover, the co-electrodeposition of nanosomes-AuNPs and PB on the sensor interface effectively amplified the electrochemical signal and maintained the activity of the receptor. The combination of ZIF-8@SWCNT with AuNPs/PB imparts excellent sensing performance of the biosensor with a wide detection range of 10^-16-10^-9 M, a low detection limit of 10^-16 M for hexanal, and a long storage stability of 15 days. These results indicate that our biosensor can be a powerful tool for versatile applications in food and other related industries.

Keywords: Hexanal; Immobilization strategy; Nanosomes; Olfactory biosensor; ZIF-8@SWCNT.

MeSH terms

Aldehydes*
Biosensing Techniques* / methods
Electrochemical Techniques
Ferrocyanides*
Gold / chemistry
Metal Nanoparticles* / chemistry

Substances

ferric ferrocyanide
Gold
n-hexanal
Aldehydes
Ferrocyanides