Longitudinal plasma proteomics in CAR T-cell therapy patients implicates neutrophils and NETosis in the genesis of CRS

Affiliations

• ¹ Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI.
• ² Department of Internal Medicine, Division of Rheumatology, University of Michigan, Ann Arbor, MI.
• ³ Department of Pediatrics, Division of Pediatric Hematology Oncology, University of Michigan, Ann Arbor, MI.
• ⁴ Johns Hopkins University School of Medicine, Baltimore, MD.
• ⁵ Division of Hematological Malignancies and Bone Marrow Transplantation, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD.
• ⁶ Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI.
• ⁷ Department of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, MI.
• ⁸ Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD.
• ⁹ Rogel Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI.
• ¹⁰ Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI.
• ¹¹ Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI.
• ¹² VA Ann Arbor Healthcare System, Ann Arbor, MI.