An unusual form of BRAF-V600E mutated hairy cell neoplasm with clinical resistance to BRAF inhibition: Challenging precision medicine

Am J Hematol. 2024 Mar;99(3):497-501. doi: 10.1002/ajh.27201. Epub 2024 Jan 24.

Abstract

Distinct outcomes of BRAF inhibition in BRAF-mutated hairy cell neoplasms with wild-type or mutant TP53, and alternative strategies to overcome mutant TP53.

Publication types

  • Letter

MeSH terms

  • Humans
  • Mutation
  • Neoplasms*
  • Precision Medicine
  • Proto-Oncogene Proteins B-raf* / genetics

Substances

  • Proto-Oncogene Proteins B-raf
  • BRAF protein, human