Immunology: Meta-learning for T cell-receptor binding specificity and beyond

Nat Mach Intell. 2023 Apr;5(4):337-339. doi: 10.1038/s42256-023-00641-5. Epub 2023 Mar 31.

Abstract

Predicting whether T-cell receptors bind to specific peptides is a challenging problem as the majority of binding examples in the training data involves only a few peptides. A new approach employs meta-learning to improve predictions for binding to peptides for which no or little binding data exists.