Microbiota Implications in Endocrine-Related Diseases: From Development to Novel Therapeutic Approaches

Biomedicines. 2024 Jan 18;12(1):221. doi: 10.3390/biomedicines12010221.

Abstract

This comprehensive review article delves into the critical role of the human microbiota in the development and management of endocrine-related diseases. We explore the complex interactions between the microbiota and the endocrine system, emphasizing the implications of microbiota dysbiosis for the onset and progression of various endocrine disorders. The review aims to synthesize current knowledge, highlighting recent advancements and the potential of novel therapeutic approaches targeting microbiota-endocrine interactions. Key topics include the impact of microbiota on hormone regulation, its role in endocrine pathologies, and the promising avenues of microbiota modulation through diet, probiotics, prebiotics, and fecal microbiota transplantation. We underscore the importance of this research in advancing personalized medicine, offering insights for more tailored and effective treatments for endocrine-related diseases.

Keywords: dysbiosis; endocrine disorders; endocrine pathology; endocrine-related cancers; gut microbiome; hormones; microbiota.

Publication types

  • Review

Grants and funding

This research received no external funding.