Metabolic dysfunction-associated fatty liver disease is becoming the most common cause of chronic liver disease worldwide, with a disease spectrum including simple steatosis, steatohepatitis, hepatic fibrosis/cirrhosis, and liver cancer. Most metabolic dysfunction-associated fatty liver diseases progress slowly, but steatohepatitis, especially in patients accompanied by significant liver fibrosis, has a significantly increased risk of adverse liver disease outcomes and all-cause death. Therefore, early-stage identification of medium-and high-risk groups carried out by stratified management has important clinical significance. Pathological diagnosis is the gold standard for diagnosing steatohepatitis and liver fibrosis. However, its invasiveness, sampling errors, and unsuitability for dynamic monitoring limit its clinical application. In recent years, a large number of non-invasive diagnostic methods based on somatology, serology, and imaging have shown great development prospects in order to meet the clinical needs of assessing disease severity and risk stratification. This article reviews and summarizes the application and progress of magnetic resonance imaging technology in the non-invasive diagnosis of metabolic dysfunction-associated fatty liver disease.
代谢相关脂肪性肝病正在成为全球范围内慢性肝病最常见的病因，其疾病谱包括单纯脂肪变性、脂肪性肝炎、肝纤维化/肝硬化以及肝癌。大多数代谢相关脂肪性肝病疾病进展缓慢，但脂肪性肝炎，尤其是伴有显著肝纤维化患者的肝病不良结局以及全因死亡风险显著增加，因此早期识别中高危人群进行分层分级管理具有重要的临床意义。病理学诊断作为诊断脂肪性肝炎以及肝纤维化的金标准，其侵入性、采样误差及不适用于动态监测等限制其在临床中的应用。为了满足评估疾病严重程度和风险分层的临床需求，近年来大量基于人体学、血清学以及影像学的无创诊断方法展现出了巨大的发展前景，现从磁共振成像技术在代谢相关脂肪性肝病无创诊断中的应用进展进行回顾和综述。.
Keywords: Magnetic resonance imaging; Metabolic associated fatty liver disease; Non-invasive diagnosis.