Dendrobium spp. were investigated for their chemical compositions with HPTLC/CMS, and biological properties, including antioxidant activities (DPPH and ABTS.+ assay), and anti-acetylcholinesterase (AChE). The ethanolic extracts of Dendrobium orchid pseudobulbs (D. chrysotoxum; DC, D. fimbriatum; DF, D. lindleyi; DL, and D. pulchellum; DP) were found to contain caffeic acid, gallic acid, quercetin, rutin hydrate and vanillin. While luteolin was shown in D. fimbriatum and D. lindleyi extracts. D. lindleyi, and D. pulchellum extracts presented the high value of total phenolic and flavonoid contents, resulting in a strong antioxidant property. Moreover, D. chrysotoxum extract expressed AChE inhibitory potential. This research indicated that chemical compounds in Dendrobium would be involved with their biological properties, i.e. antioxidant and anti-AChE. This information can be used to support further in-depth research and product development in health, food, and pharmaceutical.
Keywords: Anti-acetylcholinesterase; Dendrobium; Orchidaceae; antioxidant; flavonoids; phenolics.