Food grade plastics and Bisphenol A: Associated risks, toxicity, and bioremediation approaches

Abstract

Bisphenols' widespread use in day to day life has enabled its existence in various compartments of the environment. Bisphenol A (BPA) is utilized as a monomer in manufacturing polycarbonate plastics, epoxy resins, as well as flame retardants and is also considered as an endocrine disruptor. This study focuses on determining BPA concentration in daily-use food-grade plastic containers, in addition to its toxicity evaluation in environmental samples contaminated by BPA leachates. The highest concentration of BPA was observed in black poly bags (42.78 ppm), followed by slice juice bottles and infant milk bottles. Toxicity tests revealed significant impacts on Rhizobium and Chlorella sp. as a representative species of soil and aquatic environment respectively. To biodegrade the BPA, two potential strains, Brucella sp. and Brevibacillus parabrevis, were isolated from a landfill site. Qualitative and quantitative evaluation of biodegraded BPA through U-HPLC and GC-MSMS showed various metabolites of BPA. Results indicate the native bacterial isolates as potential candidates for BPA degradation while transforming this contaminant to a less toxic and hazardous form. The study also proposes the risk associated with food-grade plastic containers and recommends to establish a sustainable way for plastic waste management.

Keywords: Biodegradation; Bisphenol A; Food-grade Plastics; Rhizobium; Toxicity.