Surpassing sensitivity limits in liquid biopsy

Science. 2024 Jan 19;383(6680):260-261. doi: 10.1126/science.adn1886. Epub 2024 Jan 18.

Authors

Tina Moser^{1

2}, Ellen Heitzer^{1

2}

Affiliations

¹ Institute of Human Genetics, Diagnostic and Research Center for Molecular BioMedicine, Medical University of Graz, Graz, Austria.
² Christian Doppler Laboratory for Liquid Biopsies for Early Detection of Cancer, Medical University of Graz, Graz, Austria.

PMID: 38236970
DOI: 10.1126/science.adn1886

Abstract

Attenuation of cell-free DNA clearance in vivo is an alternative strategy to maximize recovery.

MeSH terms

Animals
Biomarkers, Tumor* / blood
Biomarkers, Tumor* / chemistry
Cell-Free Nucleic Acids* / blood
Cell-Free Nucleic Acids* / chemistry
Humans
Liquid Biopsy
Mice
Sensitivity and Specificity

Substances

Biomarkers, Tumor
Cell-Free Nucleic Acids