Current cannabis use and pain management among US cancer patients

Support Care Cancer. 2024 Jan 18;32(2):111. doi: 10.1007/s00520-024-08321-9.

Abstract

Background: National studies reporting the prevalence of cannabis use have focused on individuals with a history of cancer without distinction by their treatment status, which can impact symptom burden. While pain is a primary motivation to use cannabis in cancer, the magnitude of its association with cannabis use remains understudied.

Methods: We examined cannabis use and pain management among 5523 respondents of the Behavioral Risk Factor Surveillance System with a cancer history. Survey-weighted prevalence proportions of respondents' cannabis use are reported, stratified on cancer treatment status. Regression models estimated odds ratios (ORs) and 95% confidence intervals (CIs) of cancer-related pain and cannabis use.

Results: Cannabis use was slightly more prevalent in those undergoing active treatment relative to those who were not undergoing active treatment (9.3% vs. 6.2%; P=0.05). Those under active treatment were more likely to use cannabis medicinally (71.6% vs. 50.0%; P=0.03). Relative to those without cancer-related pain, persons with pain under medical control (OR 2.1, 95% CI, 1.4-3.2) or uncontrolled pain were twice as likely to use cannabis (OR 2.0, 95% CI, 1.1-3.5).

Conclusions: Use of cannabis among cancer patients may be related to their treatment and is positively associated with cancer-related pain. Future research should investigate the associations of cannabis use, symptom burden, and treatment regimens across the treatment spectrum to facilitate interventions.

Keywords: Cancer; Cannabis; Epidemiology; Marijuana; Prevalence.

MeSH terms

  • Cancer Pain* / drug therapy
  • Cancer Pain* / epidemiology
  • Cancer Pain* / etiology
  • Cannabis*
  • Humans
  • Motivation
  • Neoplasms* / complications
  • Neoplasms* / epidemiology
  • Pain / drug therapy
  • Pain / epidemiology
  • Pain / etiology
  • Pain Management