NeuroNet19: an explainable deep neural network model for the classification of brain tumors using magnetic resonance imaging data

Sci Rep. 2024 Jan 17;14(1):1524. doi: 10.1038/s41598-024-51867-1.

Abstract

Brain tumors (BTs) are one of the deadliest diseases that can significantly shorten a person's life. In recent years, deep learning has become increasingly popular for detecting and classifying BTs. In this paper, we propose a deep neural network architecture called NeuroNet19. It utilizes VGG19 as its backbone and incorporates a novel module named the Inverted Pyramid Pooling Module (iPPM). The iPPM captures multi-scale feature maps, ensuring the extraction of both local and global image contexts. This enhances the feature maps produced by the backbone, regardless of the spatial positioning or size of the tumors. To ensure the model's transparency and accountability, we employ Explainable AI. Specifically, we use Local Interpretable Model-Agnostic Explanations (LIME), which highlights the features or areas focused on while predicting individual images. NeuroNet19 is trained on four classes of BTs: glioma, meningioma, no tumor, and pituitary tumors. It is tested on a public dataset containing 7023 images. Our research demonstrates that NeuroNet19 achieves the highest accuracy at 99.3%, with precision, recall, and F1 scores at 99.2% and a Cohen Kappa coefficient (CKC) of 99%.

MeSH terms

  • Brain Neoplasms* / diagnostic imaging
  • Glioma* / diagnostic imaging
  • Humans
  • Magnetic Resonance Imaging
  • Meningeal Neoplasms*
  • Neural Networks, Computer