Eubacterium bacteremia - a retrospective observational study of a seldom found anaerobic pathogen

Diagn Microbiol Infect Dis. 2024 Apr;108(4):116185. doi: 10.1016/j.diagmicrobio.2024.116185. Epub 2024 Jan 13.

Abstract

Background: Human infections due to Eubacterium are rare and knowledge of the condition is limited. This study aimed to describe clinical characteristics and outcome in patients with Eubacterium bacteremia.

Methods: Episodes of Eubacterium bacteremia were identified through the clinical microbiology laboratory in Lund, Sweden. Medical records were retrospectively reviewed. Blood isolates of Eubacterium were collected and antibiotic susceptibility testing was performed with agar dilution.

Results: Seventeen patients with Eubacterium bacteremia were identified of whom six had monomicrobial bacteremia. The incidence was 1.7 cases of Eubacterium bacteremia per million inhabitants and year. The median age was 67 years (interquartile range 63-79 years), and six patients had some form of malignancy. Most of the patients an abdominal focus of infection and the 30-day mortality was low (n = 1).

Conclusions: Invasive infections with Eubacterium have a low incidence. The condition has a low mortality and an abdominal focus of infection, and malignancy, is common.

Keywords: Agar dilution; Anaerobic bacteria; Eubacterium; Observational study; Outcome; bacteremia.

Publication types

  • Observational Study

MeSH terms

  • Aged
  • Anaerobiosis
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia* / microbiology
  • Eubacterium
  • Humans
  • Middle Aged
  • Neoplasms*
  • Retrospective Studies

Substances

  • Anti-Bacterial Agents