Deep brain stimulation for movement disorders treatment in Africa: The current status, outcomes, and challenges

Clin Neurol Neurosurg. 2024 Jan:236:108113. doi: 10.1016/j.clineuro.2023.108113. Epub 2024 Jan 3.

Abstract

Movement disorders (MDs), a diverse group of neurological conditions characterized by abnormal and involuntary movements, have a profound impact on individuals, families, and healthcare systems. Deep Brain Stimulation (DBS) has emerged as a promising therapeutic intervention, offering relief from symptoms and improved quality of life. By implanting electrodes in specific brain regions and connecting them to a pulse generator, DBS modulates aberrant neural activity underlying these disorders. While DBS has gained recognition globally, its utilization in African countries remains limited. This comprehensive article presents the results of a literature review on the status of DBS therapy for MDs in Africa. The review assesses treatment outcomes, patient demographics, and challenges tied to implementing DBS in the African context. The findings reveal promising developments in DBS therapy across several African countries, particularly in treating Parkinson's disease and dystonia. However, challenges related to awareness, access to specialized care, and a scarcity of expertise still impede broader adoption. The article underscores the urgent need for collaborative efforts, policy changes, and increased training to expand the reach of DBS therapy, thus mitigating the burden of MDs on the African continent.

Keywords: Africa; Deep brain stimulation; Dystonia; Movement disorders; Parkinson's disease.

Publication types

  • Review

MeSH terms

  • Africa / epidemiology
  • Deep Brain Stimulation* / methods
  • Dystonic Disorders* / therapy
  • Humans
  • Movement Disorders* / therapy
  • Parkinson Disease* / therapy
  • Quality of Life
  • Treatment Outcome