Changes in frontal aslant tract tractography in selected types of brain tumours

Neurol Neurochir Pol. 2024;58(1):106-111. doi: 10.5603/pjnns.98149. Epub 2024 Jan 17.

Abstract

Aim of the study: To present differences in frontal aslant tract (FAT) tractography among patients diagnosed with primary brain tumours and metastatic brain tumours.

Material and methods: The analysis included 38 patients diagnosed with a frontal brain tumour. A control group of 30 healthy patients was also considered. The FAT was delineated, taking into account ROI 1 - the superior frontal gyrus, and ROI 2 - SMA. Endpoints were determined on the pars opercularis and pars triangularis of the inferior frontal gyrus. FAT was delineated in four different ways for each patient.

Results: In the group of patients with a brain tumour, a lower volume of FAT and a reduced quantity of fibres were observed compared to the control group. Comparison of the examined parameters between patients with glioblastoma and metastasis revealed statistically significant differences for MD (p < 0.001) regardless of the selected projection.

Conclusions: The difference in MD (mean diffusivity) among patients with metastatic tumours may be related to an increased oedema zone.

Keywords: DTI; FAT; brain tumour; tractography.

MeSH terms

  • Brain / pathology
  • Brain Mapping
  • Brain Neoplasms* / diagnostic imaging
  • Diffusion Magnetic Resonance Imaging
  • Diffusion Tensor Imaging*
  • Frontal Lobe / diagnostic imaging
  • Frontal Lobe / pathology
  • Humans