Mycobacterium avium complex pulmonary disease patients with limited treatment options

Stefano Aliberti; Francesco Blasi; Pierre-Régis Burgel; Andrea Calcagno; Andreas Fløe; Dorothy Grogono; Apostolos Papavasileiou; Eva Polverino; Concepción Prados; Gernot Rohde; Helmut J F Salzer; Adrián Sánchez-Montalvá; Michal Shteinberg; Eva Van Braeckel; Jakko van Ingen; Nicolas Veziris; Dirk Wagner; Michael R Loebinger

doi:10.1183/23120541.00610-2023

Mycobacterium avium complex pulmonary disease patients with limited treatment options

ERJ Open Res. 2024 Jan 15;10(1):00610-2023. doi: 10.1183/23120541.00610-2023. eCollection 2024 Jan.

Authors

Stefano Aliberti^{1

2}, Francesco Blasi^{3

4}, Pierre-Régis Burgel^{5

6}, Andrea Calcagno⁷, Andreas Fløe⁸, Dorothy Grogono⁹, Apostolos Papavasileiou¹⁰, Eva Polverino¹¹, Concepción Prados¹², Gernot Rohde¹³, Helmut J F Salzer^{14

15

16}, Adrián Sánchez-Montalvá^{17

18

19}, Michal Shteinberg²⁰, Eva Van Braeckel^{21

22}, Jakko van Ingen²³, Nicolas Veziris²⁴, Dirk Wagner²⁵, Michael R Loebinger²⁶

Affiliations

¹ Department of Biomedical Sciences, Humanitas University, Milan, Italy.
² IRCCS Humanitas Research Hospital, Respiratory Unit, Milan, Italy.
³ Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
⁴ Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Center, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Milano, Milan, Italy.
⁵ Respiratory Medicine, Université Paris Cité, Inserm U1016, Institut Cochin, Paris, France.
⁶ Cochin Hospital, Department of Respiratory Medicine, Publique Hôpitaux de Paris, Paris, France.
⁷ Department of Medical Sciences, Infectious Diseases, University of Turin, Turin, Italy.
⁸ Department of Respiratory Diseases, Aarhus University Hospital, Aarhus, Denmark.
⁹ Cambridge Centre of Lung Infection, Royal Papworth Hospital NHS Foundation Trust, Cambridge, UK.
¹⁰ "Sotiria" General Hospital of Chest Diseases, Athens, Greece.
¹¹ Respiratory Medicine, Adult Bronchiectasis and Cystic Fibrosis, University Hospital Vall D'Hebron, VHIR, CIBERES, Barcelona, Spain.
¹² Pulmonology, Cystic fibrosis, Bronchiectasis, Bronquial Infections, La Paz University Hospital, Madrid, Spain.
¹³ Goethe University Frankfurt, University Hospital, Medical Clinic 1, Respiratory Medicine and Allergology, Frankfurt am Main, Germany.
¹⁴ Division of Infectious Diseases and Tropical Medicine, Department of Internal Medicine 4 - Pneumology, Kepler University Hospital, Linz, Austria.
¹⁵ Medical Faculty, Johannes Kepler University Linz, Linz, Austria.
¹⁶ Ignaz Semmelweis Institute, Interuniversity Institute for Infection Research, Vienna, Austria.
¹⁷ International Health Unit Vall d'Hebron-Drassanes, Infectious Diseases Department, Vall d'Hebron University Hospital, PROSICS, Universitat Autónoma de Barcelona, Barcelona, Spain.
¹⁸ Centro de Investigación Biomédica en Red de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain.
¹⁹ Micobateria Infection Study Group (GEIM) from Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), Madrid, Spain.
²⁰ Carmel Medical Center and the Technion-Israel Institute of Technology, B. Rappaport Faculty of Medicine, Haifa, Israel.
²¹ Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium.
²² Respiratory Infection and Defense Lab (RIDL), Department of Internal Medicine and Paediatrics, Ghent University, Ghent, Belgium.
²³ Clinical Microbiologist, Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands.
²⁴ Sorbonne Université, Centre d'Immunologie et des Maladies Infectieuses (Cimi-Paris), UMR 1135, Department of Bacteriology, Saint-Antoine Hospital, APHP, Sorbonne-Université, Centre National de Référence des Mycobactéries, Paris, France.
²⁵ Department of Internal Medicine II, Division of Infectious Diseases, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
²⁶ Host Defence Unit, Royal Brompton Hospital, and NHLI, Imperial College, London, United Kingdom.

Abstract

How to identify MAC-PD patients with limited treatment options: an expert consensus https://bit.ly/3QwLQ8T.