Mantle Cell Lymphoma Presenting as Cholecystitis and Nephromegaly

Kamen W Kossow; Joseph G Bennett; Wei Cui; Aung M Tun; Robert J Kribs

doi:10.7759/cureus.50536

Mantle Cell Lymphoma Presenting as Cholecystitis and Nephromegaly

Cureus. 2023 Dec 14;15(12):e50536. doi: 10.7759/cureus.50536. eCollection 2023 Dec.

Authors

Kamen W Kossow¹, Joseph G Bennett², Wei Cui³, Aung M Tun², Robert J Kribs²

Affiliations

¹ Internal Medicine, University of Kansas Health System, Kansas City, USA.
² Hematologic Malignancies and Cellular Therapeutics, University of Kansas Health System, Westwood, USA.
³ Pathology and Laboratory Medicine, University of Kansas Health System, Kansas City, USA.

Abstract

Mantle cell lymphoma (MCL) most commonly presents as lymphadenopathy (LAD), fevers, night sweats, weight loss, splenomegaly, and blood count abnormalities. While extranodal involvement as an initial presentation can occur, it is uncommon. At initial diagnosis, MCL most commonly presents as widespread, advanced stage III or IV lymphoma. Given advanced stage MCL at presentation, it is important for medical practitioners to recognize unusual extranodal presentations of MCL for earlier diagnosis and treatment planning. Here, we present a case of MCL initially presenting as cholecystitis and bilateral nephromegaly in a 53-year-old male patient.

Keywords: cholecystitis; gallbladder; mantle cell lymphoma; nephromegaly; renal.

Publication types

Case Reports