Functional proteomics based on protein microarray technology for biomedical research

Adv Protein Chem Struct Biol. 2024:138:49-65. doi: 10.1016/bs.apcsb.2023.04.002. Epub 2023 May 15.

Abstract

This chapter traces a route through Proteomics from its origins to the present day. The different proteomics applications are discussed with a focus on microarray technology. Analytical microarrays, functional microarrays and reverse phase microarrays and their different applications are discussed. Several studies are mentioned where the great versatility of this approach is shown. Finally, the advantages and future challenges of microarray technology are outlined.

Keywords: Analytical; Functional; Microarrays; Proteome; Proteomics; Reverse-phase.

MeSH terms

  • Biomedical Research*
  • Protein Array Analysis*
  • Proteomics
  • Technology