Surgical Treatment of Brucellar Cervical Epidural Abscess

World Neurosurg. 2024 Mar:183:e838-e845. doi: 10.1016/j.wneu.2024.01.040. Epub 2024 Jan 11.

Abstract

Objectives: Brucellar cervical epidural abscess (CEA) is a rare condition with potentially permanent neurological damage if left untreated. This study aims to define the clinical presentation of brucellar CEA and evaluate the outcome of surgical treatment, specifically decompression and fusion surgery. The findings will contribute to understanding whether all patients with brucellar CEA could benefit from this surgical intervention.

Methods: A retrospective study on brucellar spondylitis was conducted at the First Hospital of Jilin University from August 2018 to August 2022. During this period, a total of 37 patients were diagnosed with brucellar spondylitis at the hospital. Out of the 37 cases, six patients (16.2%) were confirmed to have CEA through cervical magnetic resonance imaging examination and serology test results..

Results: Six patients were diagnosed with brucellar CEA (16.2%), of whom 5 successfully underwent anterior cervical decompression and fusion surgery. One patient had a large prevertebral abscess that could only be drained. In combination with effective antibiotic therapy, the clinical performance of the 5 patients who underwent surgery improved after the surgery. The remaining one patient required delayed surgery due to instability of the cervical spine. The follow-up period of all the 6 patients was 6 months.

Conclusions: Brucellosis should be considered as a potential cause of CEA, especially in endemic areas. Timely detection and effective management of this condition are crucial in order to minimize the associated morbidity and mortality. For patients with detectable brucellar CEA, we recommend decompression and fusion surgery.

Keywords: Brucellar spondylitis; Cervical epidural abscess; Medical treatment; Surgical treatment.

MeSH terms

  • Brucella*
  • Brucellosis* / complications
  • Epidural Abscess* / diagnostic imaging
  • Epidural Abscess* / drug therapy
  • Epidural Abscess* / surgery
  • Humans
  • Magnetic Resonance Imaging
  • Retrospective Studies
  • Spondylitis* / complications