Mid-term outcomes of total neointima implantation in surgical repair of acute type A aortic dissection

J Clin Hypertens (Greenwich). 2024 Feb;26(2):155-165. doi: 10.1111/jch.14762. Epub 2024 Jan 12.

Abstract

Total neointima implantation (patch neointima technique + triple-branched stent graft placement) has been performed in proximal aortic repair for acute type A aortic dissection (ATAAD) for more than 10 years at a center. However, there is no report on the mid-term outcomes with a control group of the surgical procedure. Consequently, the authors aimed to evaluate the safety and efficacy of this technique in this study. Patients who underwent the total neointima implantation were classified as Group A, and those who underwent the conventional aortic root reconstruction with the "sandwich" technique and the total aortic arch replacement were classified as Group B. Furthermore, the authors described the preoperative characteristics, operative data, and patient outcomes. Group A patients experienced a shorter surgery duration, lower volumes of perioperative bleeding, and fewer red blood cell transfusions. The incidence of neurological complications was significantly reduced in Group A. All patients maintained a normal range of proximal aortic sizes after surgery. Kaplan-Meier analysis revealed no significant differences between the patients in the two groups regarding cumulative mortality and the incidence of moderate-to-severe aortic insufficiency. In well-selected patients, total neointima implantation is an alternative procedure for the surgical repair of ATAAD.

Keywords: aortic dissection; aortic valve insufficiency; hemorrhage; postoperative complications.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aorta, Thoracic / surgery
  • Aortic Aneurysm, Thoracic* / etiology
  • Aortic Aneurysm, Thoracic* / surgery
  • Aortic Dissection* / surgery
  • Blood Vessel Prosthesis Implantation* / adverse effects
  • Blood Vessel Prosthesis Implantation* / methods
  • Humans
  • Hypertension* / etiology
  • Neointima / etiology
  • Neointima / surgery
  • Retrospective Studies
  • Stents
  • Treatment Outcome