Role of deep brain stimulation (DBS) in addiction disorders

Surg Neurol Int. 2023 Dec 22:14:434. doi: 10.25259/SNI_662_2023. eCollection 2023.

Abstract

Background: Addiction disorders pose significant challenges to public health, necessitating innovative treatments. This assesses deep brain stimulation (DBS) as a potential intervention for addiction disorders.

Methods: A literature review was carried out with a focus on the role of DBS in addiction disorders and its future implications in neurosurgical research.

Results: The online literature shows that DBS precisely modulates certain brain regions to restore addiction-related neural circuits and promote behavioral control.

Conclusion: Preclinical evidence demonstrates DBS's potential to rebalance neural circuits associated with addiction, and early clinical trials provide encouraging outcomes in enhancing addiction-related outcomes. Ethical considerations, long-term safety, and personalized patient selection require further investigation.

Keywords: Addiction; Deep brain stimulation; Health care; Neuromodulation; Nucleus accumbens; Stereotactic neurosurgery.

Publication types

  • Review