Pandemic impact on aneurysmal subarachnoid hemorrhage in Peru's high COVID-19 lethality setting: A public institutional experience

Jose Daniel Flores-Sanchez; Daniela Alejandra Perez-Chadid; John Vargas-Urbina; Jorge Zumaeta; Rommel Roger Rodriguez; Fernando Palacios; Jerson Flores-Castillo

doi:10.25259/SNI_744_2023

Pandemic impact on aneurysmal subarachnoid hemorrhage in Peru's high COVID-19 lethality setting: A public institutional experience

Surg Neurol Int. 2023 Dec 22:14:440. doi: 10.25259/SNI_744_2023. eCollection 2023.

Authors

Jose Daniel Flores-Sanchez¹, Daniela Alejandra Perez-Chadid², John Vargas-Urbina¹, Jorge Zumaeta¹, Rommel Roger Rodriguez¹, Fernando Palacios¹, Jerson Flores-Castillo¹

Affiliations

¹ Department of Neurosurgery, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Peru.
² Faculty of Medicine, Universidad CES, Medellin, Colombia.

Abstract

Background: The COVID-19 pandemic in 2020 profoundly impacted healthcare worldwide, and Peru was particularly affected, experiencing the highest COVID-19 case fatality rate globally.

Methods: We conducted a retrospective comparative study of patients presenting with aneurysmal subarachnoid hemorrhage (SAH) at a public Peruvian national referral center specializing in cerebrovascular diseases. Two study periods were considered, one during the first wave of the COVID-19 pandemic and a second identical period in 2019. Variables included patient demographics, comorbidities, COVID-19 infection status, clinical presentation, treatment approaches, and hospital outcomes.

Results: We analyzed 114 patients with aneurysmal SAH, 65 (57.0%) treated in 2019 and 49 (43.0%) in 2020. The mean time from emergency admission to the day of definitive treatment during 2019 and 2020 was 2.72 and 1.93 days, respectively. Likewise, the mean time from symptom onset to the date of definitive treatment was 6.71 and 7.70 days, respectively. We identified significant associations between complications such as sepsis, respiratory failure, acute kidney failure, and hospital mortality. The proportion of fatalities was significantly higher in 2020 compared to 2019 (36.7% vs. 15.4%, respectively). Interestingly, there was no statistically significant association between COVID-19 infection status and mortality during the 2020 period.

Conclusion: Patients with aneurysmal SAH treated during the pandemic had a higher proportion of sepsis, respiratory failure, acute kidney failure, and mortality compared to the pre-pandemic period. Reallocating healthcare resources to prioritize COVID-19 patients may have inadvertently neglected or delayed care for patients with other emergency conditions, such as aneurysmal SAH. This highlights the importance of maintaining adequate care for non-infectious emergencies during a pandemic.

Keywords: COVID-19; Global neurosurgery; Latin America; Neurosurgical capacity; Subarachnoid hemorrhage.