Primitive Neuroectodermal Tumor Presenting With a Large Subcapsular Hematoma in Pregnancy: A Case Report and Current Literature Review

Patrick Curtin; Kyler W Perry; Gabrielle Yankelevich; Robert L Grubb

doi:10.7759/cureus.50359

Primitive Neuroectodermal Tumor Presenting With a Large Subcapsular Hematoma in Pregnancy: A Case Report and Current Literature Review

Cureus. 2023 Dec 11;15(12):e50359. doi: 10.7759/cureus.50359. eCollection 2023 Dec.

Authors

Patrick Curtin¹, Kyler W Perry², Gabrielle Yankelevich¹, Robert L Grubb¹

Affiliations

¹ Department of Urology, Medical University of South Carolina, Charleston, USA.
² Department of General Surgery, Medical University of South Carolina, Charleston, USA.

Abstract

Primitive neuroectodermal tumors (PNET) are rare, small round cell tumors that are difficult to diagnose. It is important to identify PNET early, utilizing immunohistochemistry and genetic markers, as it is often an aggressive cancer. PNET is most commonly described in men between the ages of 20 and 40, with very few case reports highlighting the development in pregnant patients. We present a case of localized renal PNET in a pregnant patient and highlight the diagnostic work-up and treatment as well as the relationship between pregnancy and the potential development of aggressive tumors.

Keywords: cd-99; ewing's sarcoma family of tumors (esft); ews-fli-1; pregnancy; primitive neuroectodermal tumor (pnet).

Publication types

Case Reports