Acute generalized exanthematous pustulosis (AGEP) is an uncommon skin condition that should be considered when evaluating patients with severe skin eruptions accompanied by systemic symptoms. We present a woman in her 70s with end-stage renal disease on hemodialysis who developed a generalized pruritic rash seven days after the administration of pre-procedure vancomycin and acetaminophen. Our patient underwent a biopsy with findings consistent with AGEP. This report highlights the need to consider AGEP in patients with severe cutaneous eruptions and systemic involvement. Prompt biopsy and blood cultures are essential to prevent misdiagnosis and treatment delays.
Keywords: acetaminophen; acute generalized exanthematous pustulosis; dermatology; drug reaction; hemodialysis; internal medicine; pustular rash; staphylococcal scalded skin syndrome; vancomycin.
Copyright © 2023, Saunders Corea et al.