Polysaccharides and proteins-based bionanocomposites for microencapsulation of probiotics to improve stability and viability in the gastrointestinal tract: A review

Int J Biol Macromol. 2024 Feb;259(Pt 2):129287. doi: 10.1016/j.ijbiomac.2024.129287. Epub 2024 Jan 10.

Abstract

Probiotics have recently received significant attention due to their various benefits, such as the modulation of gut flora, reduction of blood sugar and insulin resistance, prevention and treatment of digestive disorders, and strengthening of the immune system. One of the major issues concerning probiotics is the maintenance of their viability in the presence of digestive conditions and extended shelf life during storage. To address this concern, numerous techniques have been explored to achieve success. Among these methods, the microencapsulation of probiotics has been proposed as the most effective way to overcome this challenge. The combination of nanomaterials with biopolymer coating is considered a novel approach to improve its viability and effective delivery. The use of polysaccharides and proteins-based bionanocomposites for microencapsulation of probiotics has emerged as an efficient and promising approach for maintaining cell viability and targeted delivery. This review article aims to investigate the use of different bionanocomposites in microencapsulation of probiotics and their effect on cell survival in long-term storage and harsh conditions in the gastrointestinal tract.

Keywords: Bionanocomposite; Biopolymer; Microencapsulation; Probiotic; Stability; Viability.

Publication types

  • Review

MeSH terms

  • Gastrointestinal Tract
  • Microbial Viability
  • Polysaccharides / pharmacology
  • Probiotics*

Substances

  • Polysaccharides