Titanium Alloy Implants with Lattice Structures for Mandibular Reconstruction

Khaled M Hijazi; S Jeffrey Dixon; Jerrold E Armstrong; Amin S Rizkalla

doi:10.3390/ma17010140

Titanium Alloy Implants with Lattice Structures for Mandibular Reconstruction

Materials (Basel). 2023 Dec 27;17(1):140. doi: 10.3390/ma17010140.

Authors

Khaled M Hijazi^{1

2}, S Jeffrey Dixon^{2

3}, Jerrold E Armstrong⁴, Amin S Rizkalla^{1

2

3

5}

Affiliations

¹ School of Biomedical Engineering, Faculty of Engineering, The University of Western Ontario, London, ON N6A 3K7, Canada.
² Bone and Joint Institute, The University of Western Ontario, London, ON N6G 2V4, Canada.
³ Schulich School of Medicine & Dentistry, The University of Western Ontario, London, ON N6A 5C1, Canada.
⁴ Division of Oral and Maxillofacial Surgery, Department of Otolaryngology Head and Neck Surgery, Henry Ford Hospital, Detroit, MI 48202, USA.
⁵ Chemical and Biochemical Engineering, Faculty of Engineering, The University of Western Ontario, London, ON N6A 5B9, Canada.

Abstract

In recent years, the field of mandibular reconstruction has made great strides in terms of hardware innovations and their clinical applications. There has been considerable interest in using computer-aided design, finite element modelling, and additive manufacturing techniques to build patient-specific surgical implants. Moreover, lattice implants can mimic mandibular bone's mechanical and structural properties. This article reviews current approaches for mandibular reconstruction, their applications, and their drawbacks. Then, we discuss the potential of mandibular devices with lattice structures, their development and applications, and the challenges for their use in clinical settings.

Keywords: additive manufacturing; biomaterials; finite element analysis; intraosseous; mandibular biomechanics; mandibular reconstruction; mechanical properties; porous constructs; stress shielding; titanium alloy implants.

Publication types

Review

Grants and funding

Work from the ASR laboratory is supported by the Natural Sciences and Engineering Research Council of Canada (NSERC) (Grant number: RGPIN-2017-04983), and a Collaborative Research Seed Grant from the Schulich School of Medicine & Dentistry at the University of Western Ontario.