Pore engineering of micro/mesoporous nanomaterials for encapsulation, controlled release and variegated applications of essential oils

J Control Release. 2024 Mar:367:107-134. doi: 10.1016/j.jconrel.2024.01.005. Epub 2024 Jan 25.

Abstract

Essential oils have become increasingly popular in fields of medical, food and agriculture, owing to their strongly antimicrobial, anti-inflammation and antioxidant effects, greatly meeting demand from consumers for healthy and safe natural products. However, the easy volatility and/or chemical instability of active ingredients of essential oils (EAIs) can result in the loss of activity before realizing their functions, which have greatly hindered the widely applications of EAIs. As an emerging trend, micro/mesoporous nanomaterials (MNs) have drawn great attention for encapsulation and controlled release of EAIs, owing to their tunable pore structural characteristics. In this review, we briefly discuss the recent advances of MNs that widely used in the controlled release of EAIs, including zeolites, metal-organic frameworks (MOFs), mesoporous silica nanomaterials (MSNs), and provide a comprehensive summary focusing on the pore engineering strategies of MNs that affect their controlled-release or triggered-release for EAIs, including tailorable pore structure properties (e.g., pore size, pore surface area, pore volume, pore geometry, and framework compositions) and surface properties (surface modification and surface functionalization). Finally, the variegated applications and potential challenges are also given for MNs based delivery strategies for EAIs in the fields of healthcare, food and agriculture. These will provide considerable instructions for the rational design of MNs for controlled release of EAIs.

Keywords: Application; Controlled release; Essential oils; Mesoporous nanomaterials; Pore engineering.

Publication types

  • Review

MeSH terms

  • Delayed-Action Preparations
  • Nanoparticles* / chemistry
  • Nanostructures* / chemistry
  • Oils, Volatile*
  • Porosity
  • Silicon Dioxide / chemistry

Substances

  • Delayed-Action Preparations
  • Oils, Volatile
  • Silicon Dioxide