Strategies to Maintain the Remission of Diabetes Following Metabolic Surgery

Mi Kyung Kim; Hye Soon Kim

doi:10.17476/jmbs.2023.12.2.26

Strategies to Maintain the Remission of Diabetes Following Metabolic Surgery

J Metab Bariatr Surg. 2023 Dec;12(2):26-34. doi: 10.17476/jmbs.2023.12.2.26. Epub 2023 Nov 29.

Authors

Mi Kyung Kim^{1

2}, Hye Soon Kim^{1

2}

Affiliations

¹ Department of Internal Medicine, Keimyung University School of Medicine, Dongsan Hospital, Daegu, Korea.
² Center of Bariatric and Metabolic Surgery, Keimyung University, Dongsan Hospital, Daegu, Korea.

Abstract

Obesity is a major risk factor for type 2 diabetes mellitus (T2DM). Bariatric surgery is the most effective means of inducing weight loss, and can ameliorate or induce the remission of obesity-related metabolic comorbidities, including T2DM. The guidelines for the management of T2DM emphasize weight management and recommend metabolic surgery for the treatment of T2DM accompanied by obesity. However, despite the clear beneficial effects of metabolic surgery, only 20-50% of patients who experience remission will stay in remission over the long term. Moreover, the beneficial effects of metabolic surgery tend to diminish with time, and a subset of patients experience a relapse of their diabetes. Therefore, in the present review, we discuss potential strategies for the maintenance of diabetic remission following metabolic surgery.

Keywords: Bariatric surgery; Obesity; Type 2 diabetes mellitus.

Publication types

Review