Cross-cultural validation and psychometric properties of the Spanish version of the quality of life in Childhood epilepsy Questionnaire (QOLCE-55)

Salvador Ibañez-Micó; José A López-Pina; Antonia Gómez-Conesa

doi:10.1016/j.yebeh.2023.109619

Cross-cultural validation and psychometric properties of the Spanish version of the quality of life in Childhood epilepsy Questionnaire (QOLCE-55)

Epilepsy Behav. 2024 Feb:151:109619. doi: 10.1016/j.yebeh.2023.109619. Epub 2024 Jan 8.

Authors

Salvador Ibañez-Micó¹, José A López-Pina², Antonia Gómez-Conesa³

Affiliations

¹ Pediatric Neurology Unit, Virgen de la Arrixaca University Clinic Hospital, Murcia, Spain. Electronic address: salvador.ibanez@carm.es.
² Department of Basic Psychology and Methodology, Faculty of Psychology, University of Murcia, 30100 Murcia, Spain; Research Group Research Methods and Evaluation in Social Sciences, Mare Nostrum Campus of International Excellence, University of Murcia, 30100 Murcia, Spain. Electronic address: jlpina@um.es.
³ Research Group Research Methods and Evaluation in Social Sciences, Mare Nostrum Campus of International Excellence, University of Murcia, 30100 Murcia, Spain. Electronic address: agomez@um.es.

PMID: 38194772
DOI: 10.1016/j.yebeh.2023.109619

Abstract

Objective: The aims of the present study were to translate and validate the Quality of Life in Childhood Epilepsy Questionnaire (QOLCE-55) into Spanish.

Methods: A backtranslation procedure was used to translate the English version of QOLCE-55 to Spanish, and subsequently, parents of 88 children (aged four to 12 years), completed the Spanish version of three self-reported questionnaires: the QOLCE-55, the Pediatric Quality-of-Life Inventory (PedsQL^TM 4.0), and the Pediatric Sleep Questionnaire (PSQ). Seven to 10 days later, parents completed the questionnaires again under the same conditions.

Results: Internal consistency was between 0.669 and 0.968 for the four subscales: cognitive (CF), emotional (EF), social (SF) and physical functioning (PF); and 0.954 for the total score. The test-retest reliability assessed with the intraclass correlation coefficient obtained values from 0.683 for SF to 0.962 for CF. The standard error of measurement for the total score was 5.776, and the minimal detectable change was 16.01. Spearman correlations between the total score of the Spanish version of the QOLCE-55 with the subscales was 0.760 for the CF, 0.776 for the EF, 0.799 for the SF, and 0.682 for the PF (p < 0.001). Convergent validity of QOLCE-55 with the PedsQL^TM 4.0 scale was -0.962 (p < 0.001), and the discriminant validity of the QOLCE-55 with PSQ was 0.154 (p = 0.272). This version presented a correlation with maximum lifetime consumption of anti-epileptic drugs (0.500; p < 0.001), and current consumption (0.448; p < 0.001).

Conclusions: The Spanish version of the QOLCE-55 has demonstrated adequate psychometric properties, indicating that it can be confidently used to measure the health-related quality-of-life (HRQoL) in children with epilepsy in a Spanish-speaking population. These results corroborate the instrument's cross-cultural validity.

Keywords: Epilepsy; Health-related quality of life; Minimal clinically important differenc; Translation; Validation study.

MeSH terms

Child
Cross-Cultural Comparison
Epilepsy* / psychology
Humans
Psychometrics
Quality of Life* / psychology
Reproducibility of Results
Surveys and Questionnaires