Closed-Loop Insulin Delivery May Help Prevent Metabolic Complications During Bariatric Surgery in Patients with Type 1 Diabetes: A Case Report

Diabetes Technol Ther. 2024 Apr;26(4):279-282. doi: 10.1089/dia.2023.0551.

Abstract

Introduction: Obesity in patients with type 1 diabetes (T1D) may worsen their prognosis. Bariatric surgery in these patients can be associated with complications such as diabetic ketoacidosis and severe hypoglycemic episodes. Closed-loop insulin delivery could be a solution to avoid them. Case Report: A 45-year-old woman with T1D and obesity (body mass index of 38.4 kg/m2) was included in our preoperative course of bariatric surgery. Three months before surgery, a closed-loop insulin delivery was instituted due to one prior severe hypoglycemia. Patient did not have immediate or late postoperative hypoglycemia despite consuming a weak amount of carbohydrate. Three months after surgery glycemic control was on target with 86% of time in range 70-180 mg/dL and no time below 70 mg/dL. Conclusion: This case report shows that the use of a closed-loop insulin delivery made it possible to perform bariatric surgery in complete safety for our patient.

Keywords: Bariatric surgery; Case report; Closed-loop insulin delivery; Closed-loop system; Type 1 diabetes.

Publication types

  • Case Reports

MeSH terms

  • Bariatric Surgery* / adverse effects
  • Blood Glucose / metabolism
  • Diabetes Mellitus, Type 1* / complications
  • Diabetes Mellitus, Type 1* / drug therapy
  • Diabetes Mellitus, Type 1* / surgery
  • Female
  • Humans
  • Hypoglycemia* / etiology
  • Hypoglycemia* / prevention & control
  • Hypoglycemic Agents / therapeutic use
  • Insulin / therapeutic use
  • Insulin Infusion Systems
  • Insulin, Regular, Human / therapeutic use
  • Middle Aged
  • Obesity

Substances

  • Insulin
  • Blood Glucose
  • Hypoglycemic Agents
  • Insulin, Regular, Human