[The Japanese Clinical Guidelines 2022 for Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome: An Overview]

Brain Nerve. 2024 Jan;76(1):7-12. doi: 10.11477/mf.1416202551.
[Article in Japanese]

Abstract

The new Japanese clinical guidelines for myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) were published in 2022. The Following are the salient features of these guidelines (GLs): (1)These are the first Japanese GLs that include a description of LEMS. (2)Diagnostic criteria for both MG and LEMS are described. (3)A high-dose oral steroid regimen with an escalation and de-escalation schedule is not recommended. (4)Refractory MG is defined. (5)The use of molecular-targeted drugs is included. (6)MG is subcategorized into six clinical subtypes. (7)Treatment algorithms for both MG and LEMS are discussed.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Algorithms
  • Humans
  • Japan
  • Lambert-Eaton Myasthenic Syndrome* / diagnosis
  • Lambert-Eaton Myasthenic Syndrome* / drug therapy
  • Myasthenia Gravis* / diagnosis
  • Myasthenia Gravis* / drug therapy
  • Practice Guidelines as Topic