Applications of selected polysaccharides and proteins in dentistry: A review

Int J Biol Macromol. 2024 Mar;260(Pt 1):129215. doi: 10.1016/j.ijbiomac.2024.129215. Epub 2024 Jan 6.

Abstract

In the last ten years, remarkable characteristics and a variety of functionalities have been created in biopolymeric materials for clinical dental applications. This review gives an overview of current knowledge of natural biopolymers (biological macromolecules) in terms of structural, functional, and property interactions. Natural biopolymers such as polysaccharides (chitosan, bacterial cellulose, hyaluronic acid, and alginate) and polypeptides (collagen and silk fibroin) have been discussed for dental uses. These biopolymers exhibit excellent properties alone and when employed with other composite molecules making them ideal for treatment of periodontitis, endodontics, dental pulp regeneration and oral wound healing. These biopolymers together with the composite materials exhibit better biocompatibility, inertness, elasticity and flexibility which makes them a leading candidate to be used for other dental applications like caries management, oral appliances, dentures, dental implants and oral surgeries.

Keywords: Bioactivity; Biocompatibility; Biopolymers; Dentistry; Physical properties.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials / chemistry
  • Biopolymers / chemistry
  • Collagen
  • Dental Pulp*
  • Dentistry
  • Polysaccharides / chemistry
  • Regeneration*

Substances

  • Polysaccharides
  • Biopolymers
  • Collagen
  • Biocompatible Materials