Optical coherence tomography angiography (OCTA) has extensively enhanced our comprehension of eye microcirculation and of its associated diseases. In this narrative review, we explored the key concepts behind OCTA, as well as the most recent evidence in the pathophysiology of age-related macular degeneration (AMD) made possible by OCTA. These recommendations were updated since the publication in 2020, and are targeted for 2023. Importantly, as a future perspective in OCTA technology, we will discuss how artificial intelligence has been applied to OCTA, with a particular emphasis on its application to AMD study.
Keywords: 3D OCTA; Age-related macular degeneration; Artificial intelligence; Geographic atrophy; Non-exudative macular neovascularization; Optical coherence tomography angiography; Quiescent neovascularization; Subclinical neovascularization; Type 3 macular neovascularization.
© 2024. The Author(s).