Impact of anabolic androgenic steroids on COVID-19

Steroids. 2024 Mar:203:109361. doi: 10.1016/j.steroids.2023.109361. Epub 2024 Jan 3.

Abstract

In the wake of the Novel Coronavirus arrival, the world witnessed the fragility of healthcare systems and the resilience of healthcare workers who stood on the front lines. SARS-CoV-2, also known as COVID-19 or severe acute respiratory syndrome, first appeared in China in December 2019. The infection quickly spread across the nation and the world. All countries severely restricted social interaction to stop the virus's transmission, impacting all sporting, social, and recreational activities. Anabolic androgenic steroids (AASs) are frequently used illegally to enhance strength and physical attractiveness. However, they could hurt immune system health. Much research hasn't been done yet on the connection between Covid-19 and AASs. Synthetic testosterone analogs known as anabolic androgenic steroids (AASs) can have an immune-system-altering effect. Sportspeople and bodybuilders are vulnerable to AAS abuse. Governmental reactions to the coronavirus infection issue over the last year have drawn much attention and discussion regarding public services, the experience and lessons learned from different limitations, and strategies for dealing with potential future pandemics. Using AAS has the potential to cause a variety of adverse reactions, including cardiovascular issues (including high blood pressure, heart disease, and blood clots), liver damage, renal failure, mood swings, aggressiveness, and psychiatric disorders. Individuals already suffering from severe respiratory conditions like COVID-19 may have these risks increased. This review mainly highlights the anabolic androgen steroids use and its unseen effects on coronavirus patients and gymnastics.

Keywords: Anabolic Androgenic Steroids (AAS); Covid-19; Immune system.

Publication types

  • Review

MeSH terms

  • Anabolic Agents* / adverse effects
  • Anabolic Androgenic Steroids
  • Androgens / adverse effects
  • COVID-19*
  • Humans
  • SARS-CoV-2
  • Testosterone Congeners / adverse effects

Substances

  • Androgens
  • Anabolic Androgenic Steroids
  • Anabolic Agents
  • Testosterone Congeners