Empyema caused by Streptococcus constellatus in a patient infected with HIV: a case report and literature review

AIDS Res Ther. 2024 Jan 3;21(1):2. doi: 10.1186/s12981-023-00587-z.

Abstract

Background: Empyema caused by Streptococcus constellatus (S. constellatus) is rare in patients with HIV. To analyze the clinical data of a patient living with HIV (PLHIV), who got empyema caused by S. constellatus, investigating the diagnosis and treatment of this disease through literature review to improve the clinical understanding of this disease.

Case presentation: We have reported here a 58-year-old male PLHIV with cough, wheezing, and fever for 20 days. He has a history type 2 diabetes, alcohol abuse, and a teeth extracted. Chest computed tomography revealed multiple encapsulated pleural effusions, pneumatosis, and partial compressive atelectasis in the right lung. Submission of pleural efusions timely, and then cultures revealed S. constellatus. After comprehensive treatment, including antibiotics, closed pleural drainage, and intrapleural injection of urokinase, the pleural efusion was absorbed, and chest computed tomography also confirmed the improvement.

Conclusions: S. constellatus should not be neglected as a pus pathogen in patients with HIV. comprehensive treatment is important for empyema of S. constellatus.

Keywords: Culture; Empyema; HIV; Streptococcus constellatus; Treatment.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Diabetes Mellitus, Type 2*
  • Drainage
  • Empyema, Pleural* / diagnostic imaging
  • Empyema, Pleural* / drug therapy
  • HIV Infections* / complications
  • Humans
  • Male
  • Middle Aged
  • Streptococcus constellatus*