Mannan oligosaccharides improve the fur quality of raccoon dogs by regulating the gut microbiota

Chongshan Yuan; Lili Ren; Rui Sun; Xianghong Yun; Xiao Zang; Aiwu Zhang; Min Wu

doi:10.3389/fmicb.2023.1324277

Mannan oligosaccharides improve the fur quality of raccoon dogs by regulating the gut microbiota

Front Microbiol. 2023 Dec 15:14:1324277. doi: 10.3389/fmicb.2023.1324277. eCollection 2023.

Authors

Chongshan Yuan¹, Lili Ren¹, Rui Sun¹, Xianghong Yun², Xiao Zang¹, Aiwu Zhang¹, Min Wu¹

Affiliations

¹ College of Animal Science and Technology, Jilin Agricultural University, Changchun, China.
² Animal Husbandry Research Institute, Changchun Academy of Agricultural Science, Changchun, China.

Abstract

Introduction: Adding antibiotics to animal basal diets can improve growth and production performance. However, the use of antibiotics poses a potential threat to public health safety.

Methods: The study was conducted to investigate the effects of different levels of mannan oligosaccharides (MOS) on the fur quality, nutrient apparent digestibility, serum immunity, antioxidant status, intestinal morphology, and gut microbiota of fur-growing raccoon dogs. Divide 24 male raccoon dogs (120 ± 5 d) of similar weight (5.01 ± 0.52 kg) into 4 groups randomly. Add 0, 0.05, 0.1, and 0.2% MOS to the basal diets of groups C, L, M, and H, respectively.

Results: Compared to the C group, the addition of 0.05% and 0.1% MOS in the diet increased the apparent digestibility of crude protein (CP), Underfur length (UL), Guard hair length (GL), immunoglobulin A (IgA), immunoglobulin G (IgG), and immunoglobulin M (IgM) levels in the serum (p < 0.05); Under the dosage of 0.05 % MOS, the activities of Superoxide Dismutase (SOD) and catalase (CAT) increased (p < 0.05). Compared to the C group, adding 0.05% MOS significantly increased the VH/CD of the duodenum and ileum, while also increasing the VH and CD of the jejunum (p < 0.05). Through Spearman correlation analysis of the gut microbiota, it was found that MOS can improve fur quality by reducing the abundance of Dorea while improving the immune response of raccoon dogs by reducing the abundance of Blautia and Gemmiger.

Discussion: In conclusion, MOS can improve the fur quality, serum immunity, antioxidant capacity, and gut microbiota of raccoon dogs. Therefore, MOS has the potential to replace antibiotics.

Keywords: antioxidant; fur quality; gut microbiome; immunity; mannan oligosaccharides; raccoon dogs.

Grants and funding

The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This study was completed at the Jilin Agricultural University. This study was funded by the National Key Research and Development Program of China (2018YFD0502202).