A Differential Clinical Diagnostic Challenge of a Recurrent, Oral Fibrosarcoma Resembling a Periapical Lesion of Endodontic Origin

Vasileios Zisis; Athanasios Poulopoulos; Ioannis Fotopoulos; Theodoros Lillis; Nikolaos Dabarakis; Eleftherios Anagnostou; Dimitrios Andreadis

doi:10.7759/cureus.49836

A Differential Clinical Diagnostic Challenge of a Recurrent, Oral Fibrosarcoma Resembling a Periapical Lesion of Endodontic Origin

Cureus. 2023 Dec 2;15(12):e49836. doi: 10.7759/cureus.49836. eCollection 2023 Dec.

Authors

Vasileios Zisis¹, Athanasios Poulopoulos¹, Ioannis Fotopoulos², Theodoros Lillis², Nikolaos Dabarakis², Eleftherios Anagnostou³, Dimitrios Andreadis¹

Affiliations

¹ Oral Medicine/Pathology, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC.
² Dentoalveolar Surgery, Implantology and Oral Radiology, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC.
³ Oral Medicine/ Pathology, School of Dentistry, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC.

Abstract

A fibrosarcoma is a neoplastic growth originating from malignant, fibroblast-like mesenchymal cells. This malignant tumor shows an increased tendency for expansion and recurrence and a propensity to metastasize, especially to the lungs. Despite their rarity, fibrosarcomas have the potential to manifest in any anatomical location. An oncologist referred their patient due to reported mandibular discomfort, ache, and swelling. The biopsy revealed a fibrosarcoma resembling a periapical lesion of endodontic origin. The timely intervention and the collaboration among different but complementary medical and dental specialties ensure that the patient may enjoy a prolonged life expectancy as symptom-free as possible.

Keywords: fibrosarcoma; head and neck neoplasms; immunohistochemistry staining; oral diseases; recurrent sarcoma.

Publication types

Case Reports