A dual-functional cuprum coordination framework for high proton conduction and electrochemical dopamine detection

Mingxia Zhang; Wei Tan; Xiaodan Wu; Chengan Wan; Chen Wen; Lei Feng; Feng Zhang; Fengyu Qu

doi:10.1007/s00604-023-06133-y

A dual-functional cuprum coordination framework for high proton conduction and electrochemical dopamine detection

Mikrochim Acta. 2023 Dec 30;191(1):67. doi: 10.1007/s00604-023-06133-y.

Authors

Mingxia Zhang^#¹, Wei Tan^#¹, Xiaodan Wu², Chengan Wan³, Chen Wen⁴, Lei Feng³, Feng Zhang⁵, Fengyu Qu¹

Affiliations

¹ Key Laboratory of Photochemical Biomaterials and Energy Storage Materials, Heilongjiang Province, Key Laboratory of Photonic and Electronic Bandgap Materials, Ministry of Education, Harbin Normal University, Harbin, 150025, People's Republic of China.
² Key Laboratory of Photochemical Biomaterials and Energy Storage Materials, Heilongjiang Province, Key Laboratory of Photonic and Electronic Bandgap Materials, Ministry of Education, Harbin Normal University, Harbin, 150025, People's Republic of China. smile_200325@163.com.
³ Beijing Spacecrafts Manufacturing Factory Co. Ltd., Beijing, 100094, China.
⁴ Beijing Spacecrafts Manufacturing Factory Co. Ltd., Beijing, 100094, China. wenchen@buaa.edu.cn.
⁵ Key Laboratory of Photochemical Biomaterials and Energy Storage Materials, Heilongjiang Province, Key Laboratory of Photonic and Electronic Bandgap Materials, Ministry of Education, Harbin Normal University, Harbin, 150025, People's Republic of China. zhangfeng@hrbnu.edu.cn.

^# Contributed equally.

PMID: 38159131
DOI: 10.1007/s00604-023-06133-y

Abstract

The present study selected 5, 5'-((6-(ethylamino)-1, 3, 5-triazine-2, 4-diyl) bis(azanediyl))diisophthalic acid (H₄EATDIA) as ligand and an amino-functionalized cuprum-based MOF (EA-JUC-1000), successfully synthesized by microwave-assisted method, for proton conduction and dopamine sensing applications. In order to enhance the proton-conducting potential of EA-JUC-1000, the Brönsted acid (BA) encapsulated composites (BA@EA-JUC-1000) are dopped into chitosan (CS) to form a series of hybrid membranes (BA@EA-JUC-1000/CS). The impedance results display that the best proton conductivity of CF₃SO₃H@EA-JUC-1000/CS-8% reaches up to 1.23 × 10^-3 S∙cm^-1 at 338 K and ~ 98% RH, 2.6-fold than that of CS. Moreover, the EA-JUC-1000 is in-situ combined with reduced graphene oxide (rGO) (rGO/EA-JUC-1000), which makes EA-JUC-1000 have a wide detection range (0.1 ~ 500 μM) and a low limit of detection (50 nM), together with good anti-interference performance, reproducibility and repeatability. In addition, the electrochemical sensing method has been successfully applied to detect DA in bovine serum samples. The dual-functional MOF-based hybrid membrane and composites including proton conduction and DA sensing would provide an example of practical application for MOFs.

Keywords: Cyclic voltammetry; Dopamine; EA-JUC-1000; Electrochemical sensing; Hybrid membranes; MOFs; Proton conduction.

Abstract

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