[The actual concept of salvage therapy for local recurrence prostate cancer after radical prostatectomy]

Urologiia. 2023 Dec:(6):117-121.
[Article in Russian]

Abstract

Despite highly effective radical methods of treatment of prostate cancer (PC), 30% of patients will have a biochemical recurrence. The evolution in the diagnosis of recurrent prostate cancer after prostatectomy (RP) contributes to the search and development of such methods of treatment of relapses that consider not only the effectiveness, but also the quality of life of patients. This review demonstrates the actual concept of treatment of recurrent PC after RP, starting with salvage androgen-deprivation therapy with or without EBRT, and ending with minimally invasive methods such as salvage high-dose brachytherapy.

Keywords: local recurrence; prostate cancer; prostatectomy; salvage brachytherapy; salvage radiation therapy.

Publication types

  • Review
  • English Abstract

MeSH terms

  • Androgen Antagonists
  • Brachytherapy*
  • Humans
  • Male
  • Neoplasm Recurrence, Local / surgery
  • Prostate-Specific Antigen
  • Prostatectomy / adverse effects
  • Prostatic Neoplasms* / surgery
  • Quality of Life
  • Recurrence
  • Salvage Therapy

Substances

  • Prostate-Specific Antigen
  • Androgen Antagonists