High-throughput detection and dietary exposure risk assessment of 44 mycotoxins in Mango, Litchi, Longan, and their products in South China

Hao Deng; Zhenlin Xu; Lin Luo; Yunkai Gao; Lingyu Zhou; Xiaomei Chen; Chunquan Chen; Bei Li; Qingchun Yin

doi:10.1016/j.fochx.2023.101002

High-throughput detection and dietary exposure risk assessment of 44 mycotoxins in Mango, Litchi, Longan, and their products in South China

Food Chem X. 2023 Nov 11:20:101002. doi: 10.1016/j.fochx.2023.101002. eCollection 2023 Dec 30.

Authors

Hao Deng^{1

2

3}, Zhenlin Xu⁴, Lin Luo⁴, Yunkai Gao², Lingyu Zhou², Xiaomei Chen², Chunquan Chen², Bei Li², Qingchun Yin^{1

2}

Affiliations

¹ Key Laboratory of Tropical Fruit and Vegetable Cold-Chain of Hainan Province, Institute of Agro-Products of Processing and Design, Hainan Academy of Agricultural Sciences, Haikou 571100, China.
² Key Laboratory of Tropical Fruits and Vegetables Quality and Safety for State Market Regulation, Hainan Institute for Food Control, Haikou 570311, China.
³ Key Laboratory of Genetic Resources Evaluation and Utilization of Tropical Fruits and Vegetables (Co-construction by Ministry of Province), Ministry of Agriculture and Rural Affairs, Haikou 571100, China.
⁴ Guangdong Provincial Key Laboratory of Food Quality and Safety, College of Food Science, South China Agricultural University, Guangzhou 510641, China.

Abstract

Mycotoxins exposure from food can trigger serious health hazards. This study aimed to establish an ultra-high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method for the simultaneous detection of 44 mycotoxins in fruits and their products, followed by dietary exposure risk assessment. The optimized UPLC-MS/MS method exhibited a good linear relationship with correlation coefficients ≥ 0.99041. The limits of detection (LOD) and the limits of quantification (LOQ) were within the range of 0.003 ∼ 0.700 μg/kg and 0.01 ∼ 2.00 μg/kg, respectively. The three fruits and their corresponding value-added products, with a total sampling size of 42, were subjected to analysis and detected with mycotoxins. Further dietary exposure risk assessment revealed that the hazard quotient (HQ) and hazard index (HI) of mycotoxins were 1.213 ∼ 60.032 % and 5.573 ∼ 93.750 %, indicating a low risk for Chinese consumers. However, we still need be cautious about 15-acetyl-deoxynivalenol (15-ADON), as it had 78.6 % occurrence among all samples. This work provides an accurate analysis strategy for 44 mycotoxins and contributes to mycotoxins supervision.

Keywords: Dietary exposure risk; Lichi; Longan; Mango; Mycotoxins; UPLC-MS/MS.