Background: despite years of development, response to neurostimulation remains partial and variable. Combining techniques could improve clinical efficacy and tolerance.
Objective: to examine the literature on the effects of combining several neurostimulation techniques in patients with mental disorders.
Methods: this systematic review follows the PRISMA guidelines RESULTS: 23 studies were included. The most studied combination was electroconvulsive therapy (ECT) along with another neurostimulation technique in depression. The RCTs that showed a significant effect targeted the left dorsolateral prefrontal cortex with high-frequency repetitive transcranial magnetic stimulation, before ECT. Combining neurostimulation techniques is a promising field of research.
Keywords: Combination; Electroconvulsive therapy; Neurostimulation; Psychiatric disorders; Repetitive transcranial magnetic stimulation; Transcranial direct current stimulation.
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