68 Ga-Citrate PET/CT Imaging in the Diagnosis of Skull Base Osteomyelitis and Its Usefulness in the Assessment of Treatment Response

Clin Nucl Med. 2024 Feb 1;49(2):e54-e57. doi: 10.1097/RLU.0000000000004904. Epub 2023 Dec 22.

Abstract

Purpose: 68 Ga-citrate PET/CT imaging in the diagnosis of skull base osteomyelitis (SBO) and its usefulness in the assessment of treatment response.

Methods: Eighteen patients underwent 68 Ga-citrate PET/CT scans for suspected SBO for diagnosis/assessment of treatment response.

Results: Of 18 patients, 16 patients had a positive study for SBO, and 2 patients had a negative study. Scan findings were correlated with clinical, biochemical, microbiological, and radiological parameters.

Conclusion: 68 Ga-citrate PET/CT is a promising tool in the diagnosis and management of skull base osteomyelitis.

MeSH terms

  • Citrates
  • Humans
  • Osteomyelitis* / diagnostic imaging
  • Osteomyelitis* / therapy
  • Positron Emission Tomography Computed Tomography* / methods
  • Skull Base / diagnostic imaging

Substances

  • gallium citrate
  • Citrates