Sphingolipids are involved in cell signaling and metabolic pathways, and their metabolites play a critical role in host defense against intracellular pathogens. Here, we review the known mechanisms of sphingolipids in viral infections and discuss the potential implication of the study of sphingolipid metabolism in vaccine and therapeutic development.
Keywords: lipid metabolism; sphingolipid metabolism; sphingolipids; sphingosine-1-phosphate; viral infections.