Advances in Detection Techniques for the H5N1 Avian Influenza Virus

Int J Mol Sci. 2023 Dec 5;24(24):17157. doi: 10.3390/ijms242417157.

Abstract

Avian influenza is caused by avian influenza virus infection; the H5N1 avian influenza virus is a highly pathogenic subtype, affecting poultry and human health. Since the discovery of the highly pathogenic subtype of the H5N1 avian influenza virus, it has caused enormous losses to the poultry farming industry. It was recently found that the H5N1 avian influenza virus tends to spread among mammals. Therefore, early rapid detection methods are highly significant for effectively preventing the spread of H5N1. This paper discusses the detection technologies used in the detection of the H5N1 avian influenza virus, including serological detection technology, immunological detection technology, molecular biology detection technology, genetic detection technology, and biosensors. Comparisons of these detection technologies were analyzed, aiming to provide some recommendations for the detection of the H5N1 avian influenza virus.

Keywords: H5N1 subtype; avian influenza virus; detection technology.

Publication types

  • Review

MeSH terms

  • Agriculture
  • Animals
  • Humans
  • Influenza A Virus, H5N1 Subtype* / genetics
  • Influenza A virus*
  • Influenza in Birds* / diagnosis
  • Mammals
  • Poultry