Recent Progress in Advanced Polyester Elastomers for Tissue Engineering and Bioelectronics

Molecules. 2023 Dec 9;28(24):8025. doi: 10.3390/molecules28248025.

Abstract

Polyester elastomers are highly flexible and elastic materials that have demonstrated considerable potential in various biomedical applications including cardiac, vascular, neural, and bone tissue engineering and bioelectronics. Polyesters are desirable candidates for future commercial implants due to their biocompatibility, biodegradability, tunable mechanical properties, and facile synthesis and fabrication methods. The incorporation of bioactive components further improves the therapeutic effects of polyester elastomers in biomedical applications. In this review, novel structural modification methods that contribute to outstanding mechanical behaviors of polyester elastomers are discussed. Recent advances in the application of polyester elastomers in tissue engineering and bioelectronics are outlined and analyzed. A prospective of the future research and development on polyester elastomers is also provided.

Keywords: bioelectronics; elastomers; polyester; tissue engineering.

Publication types

  • Review

MeSH terms

  • Biocompatible Materials / chemistry
  • Elastomers* / chemistry
  • Polyesters* / chemistry
  • Tissue Engineering / methods

Substances

  • Elastomers
  • Polyesters
  • Biocompatible Materials

Grants and funding

This work was funded by NSERC (Natural Sciences and Engineering Research Council of Canada).