Aggressive Male Breast Cancer-Clinical and Therapeutic Aspects Correlated with the Histopathological Examination: A Case Report and Literature Review

Medicina (Kaunas). 2023 Dec 14;59(12):2167. doi: 10.3390/medicina59122167.

Abstract

Breast cancer is often seen as a disease that occurs in women, but it can also appear in men in a very small percentage, below 1%. Men have a minimal amount of breast tissue compared to women, which has the potential to become malignant in a similar way to women, although much less frequently. A patient presented with advanced local invasion due to the low amount of breast tissue, with the tumor quickly invading the adjacent structures. Histopathological and immunohistochemical examinations have an extremely important role in the pathology of breast cancer. Given that male breast cancer is rare and there are not enough surgeons specializing in breast surgery in our country, there is a lack of experience in the management and early diagnosis of this type of cancer, which will be highlighted in this article.

Keywords: histopathological examination; immunohistochemical reactions; male breast cancer; treatment.

Publication types

  • Review
  • Case Reports

MeSH terms

  • Breast Neoplasms* / pathology
  • Breast Neoplasms, Male* / pathology
  • Breast Neoplasms, Male* / surgery
  • Female
  • Humans
  • Male

Grants and funding

This research received no external funding.