The experiences of adjuvant endocrine therapy for women breast cancer survivors: A literature review

Medicine (Baltimore). 2023 Dec 22;102(51):e36704. doi: 10.1097/MD.0000000000036704.

Abstract

Introduction: Adjuvant endocrine therapy (AET) is commonly recommended for non-metastatic breast cancer survivors. However, the side-effects associated with AET can have a negative impact on survivors' functional status and quality of life. Understanding the factors influencing adherence to AET is crucial in improving its utilization among female breast cancer survivors.

Conclusions: This literature review critically evaluated 15 articles to explore the experiences of female breast cancer survivors in adhering to and persisting with AET. The findings highlight that while AET can cause drug side-effects, the involvement of healthcare professionals (HCP) plays a significant role in facilitating better use of AET. Unfortunately, many HCP fail to discuss vital information related to AET or provide guidance on managing side-effects and daily medication. Consequently, survivors often lack guidance in these areas. Despite experiencing discomfort, survivors maintain a positive attitude towards using AET and employ self-management strategies and social networks to overcome barriers. The impact of HCP on AET adherence among female breast cancer survivors is substantial. Future research should focus on understanding perspectives that promote HCP involvement, which will inform practical intervention strategies in clinical practice.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents, Hormonal / adverse effects
  • Breast Neoplasms* / drug therapy
  • Cancer Survivors*
  • Chemotherapy, Adjuvant / adverse effects
  • Female
  • Humans
  • Medication Adherence
  • Quality of Life
  • Survivors

Substances

  • Antineoplastic Agents, Hormonal